About Transcriptional adapter 1
Transcriptional adapter 1 (TADA1) is a protein
from Homo sapiens identified by UniProt accession
Q96BN2, 335 residues long.
MolForge cross-references it against 0 known binders and
19 disease associations.
Target properties
| Protein name | Transcriptional adapter 1 |
|---|
| UniProt accession | Q96BN2 |
|---|
| Gene | TADA1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 335 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (19)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.49
- neurodegenerative disease · score 0.36
- platelet count · score 0.35
- platelet component distribution width · score 0.29
- neutrophil count · score 0.27
- leukocyte count · score 0.26
- myeloid white cell count · score 0.17
- ovarian carcinoma · score 0.15
- sex hormone-binding globulin measurement · score 0.14
- neutrophil percentage of leukocytes · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96BN2-F1 | alphafold | PREDICTED | 77.03 | — |
Amino-acid sequence (335 residues)
MATFVSELEA AKKNLSEALG DNVKQYWANL KLWFKQKISK EEFDLEAHRL LTQDNVHSHN DFLLAILTRC QILVSTPDGA GSLPWPGGSA AKPGKPKGKK KLSSVRQKFD HRFQPQNPLS GAQQFVAKDP QDDDDLKLCS HTMMLPTRGQ LEGRMIVTAY EHGLDNVTEE AVSAVVYAVE NHLKDILTSV VSRRKAYRLR DGHFKYAFGS NVTPQPYLKN SVVAYNNLIE SPPAFTAPCA GQNPASHPPP DDAEQQAALL LACSGDTLPA SLPPVNMYDL FEALQVHREV IPTHTVYALN IERIITKLWH PNHEELQQDK VHRQRLAAKE GLLLC
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