About Calcineurin B homologous protein 3
Calcineurin B homologous protein 3 (TESC) is a protein
from Homo sapiens identified by UniProt accession
Q96BS2, 214 residues long.
MolForge cross-references it against 0 known binders and
80 disease associations.
Target properties
| Protein name | Calcineurin B homologous protein 3 |
|---|
| UniProt accession | Q96BS2 |
|---|
| Gene | TESC |
|---|
| Organism | Homo sapiens |
|---|
| Length | 214 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (80)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.45
- cortical thickness · score 0.38
- self reported educational attainment · score 0.38
- PR interval · score 0.38
- platelet crit · score 0.37
- lifestyle measurement · score 0.31
- neurodegenerative disease · score 0.21
- protein measurement · score 0.07
- hemoglobin measurement · score 0.07
- lean body mass · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96BS2-F1 | alphafold | PREDICTED | 86.31 | — |
Amino-acid sequence (214 residues)
MGAAHSASEE VRELEGKTGF SSDQIEQLHR RFKQLSGDQP TIRKENFNNV PDLELNPIRS KIVRAFFDNR NLRKGPSGLA DEINFEDFLT IMSYFRPIDT TMDEEQVELS RKEKLRFLFH MYDSDSDGRI TLEEYRNVVE ELLSGNPHIE KESARSIADG AMMEAASVCM GQMEPDQVYE GITFEDFLKI WQGIDIETKM HVRFLNMETM ALCH
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