S100P-binding protein (S100PBP)

About S100P-binding protein

S100P-binding protein (S100PBP) is a protein from Homo sapiens identified by UniProt accession Q96BU1, 408 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.

Target properties

Protein name	S100P-binding protein
UniProt accession	Q96BU1
Gene	S100PBP
Organism	Homo sapiens
Length	408 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (29)

Diseases linked to this target (Open Targets).

neurologic, endocrine, and pancreatic disease, multisystem, infantile-onset · score 0.27
Charcot-Marie-Tooth disease dominant intermediate C · score 0.19
body mass index · score 0.15
daytime rest measurement · score 0.12
genetic disorder · score 0.12
excessive daytime sleepiness measurement · score 0.12
visceral adipose tissue measurement · score 0.11
body height · score 0.10
lean body mass · score 0.09
body weight · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96BU1-F1	alphafold	PREDICTED	53.85	—

Amino-acid sequence (408 residues)

MMCSRVPSEQ SSGTSLLPKD GAPFSWDSLD EDGLDDSLLE LSEGEEDDGD VNYTEEEIDA LLKEDDPSYE QSSGEDDGGH VEKGERGSQI LLDTPREKNS SYSLGPVAET PDLFKLPQLS TSSGHGPAHT KPLNRRSVLE KNLIKVTVAP FNPTVCDALL DKDETDSSKD TEKLSSLGEE MREDGLSPNE SKLCTESEGI SPNNSAWNGP QLSSSNNNFQ QTVSDKNMPD SENPTSVFSR ISDHSETPNM ELSCRNGGSH KSSCEMRSLV VSTSSNKQDV LNKDSGKMKG HERRLGKVIP VLQTKTRTNV PTFSQSNLEQ QKQLYLRSVI AHIEDPEDTN QGISGELCAL MDQVHHMQHS KWQHPSDLTT RNYARRQKHL QRYSLTQWVD RNMRSHHRFQ RLPDFSYS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards