N-acetyltaurine hydrolase (PTER)

About N-acetyltaurine hydrolase

N-acetyltaurine hydrolase (PTER) is a protein from Homo sapiens identified by UniProt accession Q96BW5, 349 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.

Target properties

Protein name	N-acetyltaurine hydrolase
UniProt accession	Q96BW5
Gene	PTER
Organism	Homo sapiens
Length	349 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (54)

Diseases linked to this target (Open Targets).

serum metabolite measurement · score 0.34
metabolite measurement · score 0.29
N-acetyl-beta-alanine measurement · score 0.28
PHF-tau measurement · score 0.16
amyloid-beta measurement · score 0.09
melanoma · score 0.07
osteoporosis · score 0.05
Osteoporosis · score 0.05
melorheostosis · score 0.05
dacryocystitis-osteopoikilosis syndrome · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96BW5-F1	alphafold	PREDICTED	97.58	—

Amino-acid sequence (349 residues)

MSSLSGKVQT VLGLVEPSKL GRTLTHEHLA MTFDCCYCPP PPCQEAISKE PIVMKNLYWI QKNAYSHKEN LQLNQETEAI KEELLYFKAN GGGALVENTT TGISRDTQTL KRLAEETGVH IISGAGFYVD ATHSSETRAM SVEQLTDVLM NEILHGADGT SIKCGIIGEI GCSWPLTESE RKVLQATAHA QAQLGCPVII HPGRSSRAPF QIIRILQEAG ADISKTVMSH LDRTILDKKE LLEFAQLGCY LEYDLFGTEL LHYQLGPDID MPDDNKRIRR VRLLVEEGCE DRILVAHDIH TKTRLMKYGG HGYSHILTNV VPKMLLRGIT ENVLDKILIE NPKQWLTFK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards