Zinc finger and BTB domain-containing protein 9…

About Zinc finger and BTB domain-containing protein 9

Zinc finger and BTB domain-containing protein 9 (ZBTB9) is a protein from Homo sapiens identified by UniProt accession Q96C00, 473 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

Target properties

Protein name	Zinc finger and BTB domain-containing protein 9
UniProt accession	Q96C00
Gene	ZBTB9
Organism	Homo sapiens
Length	473 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (44)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.39
multiple sclerosis · score 0.35
Parkinson disease · score 0.32
Alzheimer disease · score 0.32
lysosomal storage disease · score 0.32
type 1 diabetes mellitus · score 0.24
systolic blood pressure · score 0.14
celiac disease · score 0.12
diet measurement · score 0.10
leukocyte count · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96C00-F1	alphafold	PREDICTED	59.43	—

Amino-acid sequence (473 residues)

METPTPLPPV PASPTCNPAP RTIQIEFPQH SSSLLESLNR HRLEGKFCDV SLLVQGRELR AHKAVLAAAS PYFHDKLLLG DAPRLTLPSV IEADAFEGLL QLIYSGRLRL PLDALPAHLL VASGLQMWQV VDQCSEILRE LETSGGGISA RGGNSYHALL STTSSTGGWC IRSSPFQTPV QSSASTESPA STESPVGGEG SELGEVLQIQ VEEEEEEEED DDDEDQGSAT LSQTPQPQRV SGVFPRPHGP HPLPMTATPR KLPEGESAPL ELPAPPALPP KIFYIKQEPF EPKEEISGSG TQPGGAKEET KVFSGGDTEG NGELGFLLPS GPGPTSGGGG PSWKPVDLHG NEILSGGGGP GGAGQAVHGP VKLGGTPPAD GKRFGCLCGK RFAVKPKRDR HIMLTFSLRP FGCGICNKRF KLKHHLTEHM KTHAGALHAC PHCGRRFRVH ACFLRHRDLC KGQGWATAHW TYK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Zinc finger and BTB domain-containing protein 9 (ZBTB9)