About FGGY carbohydrate kinase domain-containing protein
FGGY carbohydrate kinase domain-containing protein (FGGY) is a protein
from Homo sapiens identified by UniProt accession
Q96C11, 551 residues long.
MolForge cross-references it against 0 known binders and
65 disease associations.
Target properties
| Protein name | FGGY carbohydrate kinase domain-containing protein |
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| UniProt accession | Q96C11 |
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| Gene | FGGY |
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| Organism | Homo sapiens |
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| Length | 551 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (65)
Diseases linked to this target (Open Targets).
- pulse pressure measurement · score 0.43
- systolic blood pressure · score 0.38
- sporadic amyotrophic lateral sclerosis · score 0.37
- familial amyotrophic lateral sclerosis · score 0.37
- neuroinflammatory disorder · score 0.37
- hematocrit · score 0.35
- aspartate aminotransferase measurement · score 0.34
- neurodegenerative disease · score 0.33
- lysosomal storage disease · score 0.33
- Alzheimer disease · score 0.33
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96C11-F1 | alphafold | PREDICTED | 96.00 | — |
Amino-acid sequence (551 residues)
MSGGEQKPER YYVGVDVGTG SVRAALVDQS GVLLAFADQP IKNWEPQFNH HEQSSEDIWA ACCVVTKKVV QGIDLNQIRG LGFDATCSLV VLDKQFHPLP VNQEGDSHRN VIMWLDHRAV SQVNRINETK HSVLQYVGGV MSVEMQAPKL LWLKENLREI CWDKAGHFFD LPDFLSWKAT GVTARSLCSL VCKWTYSAEK GWDDSFWKMI GLEDFVADNY SKIGNQVLPP GASLGNGLTP EAARDLGLLP GIAVAASLID AHAGGLGVIG ADVRGHGLIC EGQPVTSRLA VICGTSSCHM GISKDPIFVP GVWGPYFSAM VPGFWLNEGG QSVTGKLIDH MVQGHAAFPE LQVKATARCQ SIYAYLNSHL DLIKKAQPVG FLTVDLHVWP DFHGNRSPLA DLTLKGMVTG LKLSQDLDDL AILYLATVQA IALGTRFIIE AMEAAGHSIS TLFLCGGLSK NPLFVQMHAD ITGMPVVLSQ EVESVLVGAA VLGACASGDF ASVQEAMAKM SKVGKVVFPR LQDKKYYDKK YQVFLKLVEH QKEYLAIMND D
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