About Galactose mutarotase
Galactose mutarotase (GALM) is a protein
from Homo sapiens identified by UniProt accession
Q96C23, 342 residues long.
MolForge cross-references it against 0 known binders and
51 disease associations.
Target properties
| Protein name | Galactose mutarotase |
|---|
| UniProt accession | Q96C23 |
|---|
| Gene | GALM |
|---|
| Organism | Homo sapiens |
|---|
| Length | 342 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (51)
Diseases linked to this target (Open Targets).
- galactosemia 4 · score 0.72
- lymphocyte count · score 0.51
- blood protein measurement · score 0.46
- protein measurement · score 0.42
- monocyte count · score 0.27
- genetic disorder · score 0.19
- body height · score 0.12
- schizophrenia · score 0.11
- metabolite measurement · score 0.04
- Red cell distribution width · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96C23-F1 | alphafold | PREDICTED | 97.74 | — |
Amino-acid sequence (342 residues)
MASVTRAVFG ELPSGGGTVE KFQLQSDLLR VDIISWGCTI TALEVKDRQG RASDVVLGFA ELEGYLQKQP YFGAVIGRVA NRIAKGTFKV DGKEYHLAIN KEPNSLHGGV RGFDKVLWTP RVLSNGVQFS RISPDGEEGY PGELKVWVTY TLDGGELIVN YRAQASQATP VNLTNHSYFN LAGQASPNIN DHEVTIEADT YLPVDETLIP TGEVAPVQGT AFDLRKPVEL GKHLQDFHLN GFDHNFCLKG SKEKHFCARV HHAASGRVLE VYTTQPGVQF YTGNFLDGTL KGKNGAVYPK HSGFCLETQN WPDAVNQPRF PPVLLRPGEE YDHTTWFKFS VA
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