About Protein CUSTOS
Protein CUSTOS (CUSTOS) is a protein
from Homo sapiens identified by UniProt accession
Q96C57, 262 residues long.
MolForge cross-references it against 0 known binders and
94 disease associations.
Target properties
| Protein name | Protein CUSTOS |
|---|
| UniProt accession | Q96C57 |
|---|
| Gene | CUSTOS |
|---|
| Organism | Homo sapiens |
|---|
| Length | 262 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (94)
Diseases linked to this target (Open Targets).
- monogenic diabetes · score 0.53
- maturity-onset diabetes of the young type 3 · score 0.50
- maturity-onset diabetes of the young · score 0.36
- MODY · score 0.36
- gestational diabetes · score 0.33
- Maternal diabetes · score 0.33
- type 2 diabetes mellitus · score 0.33
- N-glycan measurement · score 0.26
- diabetes mellitus · score 0.25
- hemoglobin measurement · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96C57-F1 | alphafold | PREDICTED | 63.29 | — |
Amino-acid sequence (262 residues)
MAAPSGTVSD SESSNSSSDA EELERCREAA MPAWGLEQRP HVAGKPRAGA ANSQLSTSQP SLRHKVNEHE QDGNELQTTP EFRAHVAKKL GALLDSFITI SEAAKEPAKA KVQKVALEDD GFRLFFTSVP GGREKEESPQ PRRKRQPSSS SEDSDEEWRR CREAAVSASD ILQESAIHSP GTVEKEAKKK RKLKKKAKKV ASVDSAVAAT TPTSMATVQK QKSGELNGDQ VSLGTKKKKK AKKASETSPF PPAKSATAIP AN
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