About Ropporin-1-like protein
Ropporin-1-like protein (ROPN1L) is a protein
from Homo sapiens identified by UniProt accession
Q96C74, 230 residues long.
MolForge cross-references it against 0 known binders and
43 disease associations.
Target properties
| Protein name | Ropporin-1-like protein |
|---|
| UniProt accession | Q96C74 |
|---|
| Gene | ROPN1L |
|---|
| Organism | Homo sapiens |
|---|
| Length | 230 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (43)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.10
- eosinophil percentage of leukocytes · score 0.09
- ovarian neoplasm · score 0.07
- sum of eosinophil and basophil counts · score 0.06
- eosinophil percentage of granulocytes · score 0.06
- Hypomaturation amelogenesis imperfecta · score 0.05
- amelogenesis imperfecta · score 0.04
- X-linked non-syndromic intellectual disability · score 0.04
- Hypoplastic amelogenesis imperfecta · score 0.04
- tooth agenesis · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96C74-F1 | alphafold | PREDICTED | 85.71 | — |
Amino-acid sequence (230 residues)
MPLPDTMFCA QQIHIPPELP DILKQFTKAA IRTQPADVLR WSAGYFSALS RGDPLPVKDR MEMPTATQKT DTGLTQGLLK VLHKQCHHKR YVELTDLEQK WKNLCLPKEK FKALLQLDPC ENKIKWINFL ALGCSMLGGS LNTALKHLCE ILTDDPEGGP ARIPFKTFSY VYRYLARLDS DVSPLETESY LASLKENIDA RKNGMIGLSD FFFPKRKLLE SIENSEDVGH
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