m7GpppX diphosphatase (DCPS)

About m7GpppX diphosphatase

m7GpppX diphosphatase (DCPS) is a protein from Homo sapiens identified by UniProt accession Q96C86, 337 residues long. MolForge cross-references it against 0 known binders and 148 disease associations.

Target properties

Protein name	m7GpppX diphosphatase
UniProt accession	Q96C86
Gene	DCPS
Organism	Homo sapiens
Length	337 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (148)

Diseases linked to this target (Open Targets).

autosomal recessive non-syndromic intellectual disability · score 0.65
neurodegenerative disease · score 0.57
neuroinflammatory disorder · score 0.43
eosinophil count · score 0.30
ST2 protein measurement · score 0.24
neutrophil percentage of leukocytes · score 0.20
neutrophil count · score 0.20
interleukin 1 receptor-like 1 measurement · score 0.19
genetic disorder · score 0.19
low density lipoprotein cholesterol measurement · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96C86-F1	alphafold	PREDICTED	88.37	—

Amino-acid sequence (337 residues)

MADAAPQLGK RKRELDVEEA HAASTEEKEA GVGNGTCAPV RLPFSGFRLQ KVLRESARDK IIFLHGKVNE ASGDGDGEDA VVILEKTPFQ VEQVAQLLTG SPELQLQFSN DIYSTYHLFP PRQLNDVKTT VVYPATEKHL QKYLRQDLRL IRETGDDYRN ITLPHLESQS LSIQWVYNIL DKKAEADRIV FENPDPSDGF VLIPDLKWNQ QQLDDLYLIA ICHRRGIRSL RDLTPEHLPL LRNILHQGQE AILQRYRMKG DHLRVYLHYL PSYYHLHVHF TALGFEAPGS GVERAHLLAE VIENLECDPR HYQQRTLTFA LRADDPLLKL LQEAQQS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards