About Phosphopantothenoylcysteine decarboxylase
Phosphopantothenoylcysteine decarboxylase (PPCDC) is a protein
from Homo sapiens identified by UniProt accession
Q96CD2, 204 residues long.
MolForge cross-references it against 0 known binders and
56 disease associations.
Target properties
| Protein name | Phosphopantothenoylcysteine decarboxylase |
|---|
| UniProt accession | Q96CD2 |
|---|
| Gene | PPCDC |
|---|
| Organism | Homo sapiens |
|---|
| Length | 204 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (56)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- leukocyte count · score 0.32
- neutrophil count · score 0.32
- mean corpuscular volume · score 0.31
- platelet count · score 0.29
- mean corpuscular hemoglobin concentration · score 0.25
- hematocrit · score 0.23
- mean reticulocyte volume · score 0.22
- serum zinc measurement · score 0.20
- Eczematoid dermatitis · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96CD2-F1 | alphafold | PREDICTED | 90.58 | — |
Amino-acid sequence (204 residues)
MEPKASCPAA APLMERKFHV LVGVTGSVAA LKLPLLVSKL LDIPGLEVAV VTTERAKHFY SPQDIPVTLY SDADEWEIWK SRSDPVLHID LRRWADLLLV APLDANTLGK VASGICDNLL TCVMRAWDRS KPLLFCPAMN TAMWEHPITA QQVDQLKAFG YVEIPCVAKK LVCGDEGLGA MAEVGTIVDK VKEVLFQHSG FQQS
Explore Phosphopantothenoylcysteine decarboxylase with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets