About Transmembrane 4 L6 family member 18
Transmembrane 4 L6 family member 18 (TM4SF18) is a protein
from Homo sapiens identified by UniProt accession
Q96CE8, 201 residues long.
MolForge cross-references it against 0 known binders and
40 disease associations.
Target properties
| Protein name | Transmembrane 4 L6 family member 18 |
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| UniProt accession | Q96CE8 |
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| Gene | TM4SF18 |
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| Organism | Homo sapiens |
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| Length | 201 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (40)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.38
- platelet component distribution width · score 0.33
- platelet count · score 0.29
- platelet crit · score 0.29
- hypothyroidism · score 0.22
- cannabis dependence measurement · score 0.22
- adolescent idiopathic scoliosis · score 0.21
- gonorrhea · score 0.07
- serum alanine aminotransferase measurement · score 0.04
- serum gamma-glutamyl transferase measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96CE8-F1 | alphafold | PREDICTED | 79.55 | — |
Amino-acid sequence (201 residues)
MGSRKCGGCL SCLLIPLALW SIIVNILLYF PNGQTSYASS NKLTNYVWYF EGICFSGIMM LIVTTVLLVL ENNNNYKCCQ SENCSKKYVT LLSIIFSSLG IAFSGYCLVI SALGLVQGPY CRTLDGWEYA FEGTAGRFLT DSSIWIQCLE PAHVVEWNII LFSILITLSG LQVIICLIRV VMQLSKILCG SYSVIFQPGI I
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