About Charged multivesicular body protein 4c
Charged multivesicular body protein 4c (CHMP4C) is a protein
from Homo sapiens identified by UniProt accession
Q96CF2, 233 residues long.
MolForge cross-references it against 0 known binders and
69 disease associations.
Target properties
| Protein name | Charged multivesicular body protein 4c |
|---|
| UniProt accession | Q96CF2 |
|---|
| Gene | CHMP4C |
|---|
| Organism | Homo sapiens |
|---|
| Length | 233 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (69)
Diseases linked to this target (Open Targets).
- viral disease · score 0.46
- HIV infection · score 0.46
- ovarian carcinoma · score 0.42
- COVID-19 · score 0.37
- severe acute respiratory syndrome · score 0.37
- ovarian serous carcinoma · score 0.37
- cystatin C measurement · score 0.30
- age-related hearing impairment · score 0.30
- blood phosphate measurement · score 0.30
- malignant epithelial tumor of ovary · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96CF2-F1 | alphafold | PREDICTED | 76.45 | — |
Amino-acid sequence (233 residues)
MSKLGKFFKG GGSSKSRAAP SPQEALVRLR ETEEMLGKKQ EYLENRIQRE IALAKKHGTQ NKRAALQALK RKKRFEKQLT QIDGTLSTIE FQREALENSH TNTEVLRNMG FAAKAMKSVH ENMDLNKIDD LMQEITEQQD IAQEISEAFS QRVGFGDDFD EDELMAELEE LEQEELNKKM TNIRLPNVPS SSLPAQPNRK PGMSSTARRS RAASSQRAEE EDDDIKQLAA WAT
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