About TRAF-interacting protein with FHA domain-containing protein A
TRAF-interacting protein with FHA domain-containing protein A (TIFA) is a protein
from Homo sapiens identified by UniProt accession
Q96CG3, 184 residues long.
MolForge cross-references it against 0 known binders and
32 disease associations.
Target properties
| Protein name | TRAF-interacting protein with FHA domain-containing protein A |
|---|
| UniProt accession | Q96CG3 |
|---|
| Gene | TIFA |
|---|
| Organism | Homo sapiens |
|---|
| Length | 184 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (32)
Diseases linked to this target (Open Targets).
- neuritic plaque measurement · score 0.13
- serum gamma-glutamyl transferase measurement · score 0.12
- body mass index · score 0.10
- insomnia measurement · score 0.07
- mathematical ability · score 0.07
- rheumatoid arthritis · score 0.06
- adolescent idiopathic scoliosis · score 0.06
- lean body mass · score 0.06
- body height · score 0.05
- lymphocyte count · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96CG3-F1 | alphafold | PREDICTED | 86.59 | — |
Amino-acid sequence (184 residues)
MTSFEDADTE ETVTCLQMTV YHPGQLQCGI FQSISFNREK LPSSEVVKFG RNSNICHYTF QDKQVSRVQF SLQLFKKFNS SVLSFEIKNM SKKTNLIVDS RELGYLNKMD LPYRCMVRFG EYQFLMEKED GESLEFFETQ FILSPRSLLQ ENNWPPHRPI PEYGTYSLCS SQSSSPTEMD ENES
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