About Nucleoredoxin-like protein 1
Nucleoredoxin-like protein 1 (NXNL1) is a protein
from Homo sapiens identified by UniProt accession
Q96CM4, 212 residues long.
MolForge cross-references it against 0 known binders and
13 disease associations.
Target properties
| Protein name | Nucleoredoxin-like protein 1 |
|---|
| UniProt accession | Q96CM4 |
|---|
| Gene | NXNL1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 212 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (13)
Diseases linked to this target (Open Targets).
- atopic eczema · score 0.08
- retinitis pigmentosa · score 0.01
- retinal degeneration · score 0.01
- retinoblastoma · score 0.01
- age-related macular degeneration · score 0.01
- Alzheimer disease · score 0.00
- retinitis · score 0.00
- cancer · score 0.00
- Cone rod dystrophy · score 0.00
- respiratory distress syndrome in premature infants · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96CM4-F1 | alphafold | PREDICTED | 73.83 | — |
Amino-acid sequence (212 residues)
MASLFSGRIL IRNNSDQDEL DTEAEVSRRL ENRLVLLFFG AGACPQCQAF VPILKDFFVR LTDEFYVLRA AQLALVYVSQ DSTEEQQDLF LKDMPKKWLF LPFEDDLRRD LGRQFSVERL PAVVVLKPDG DVLTRDGADE IQRLGTACFA NWQEAAEVLD RNFQLPEDLE DQEPRSLTEC LRRHKYRVEK AARGGRDPGG GGGEEGGAGG LF
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