About FLYWCH family member 2
FLYWCH family member 2 (FLYWCH2) is a protein
from Homo sapiens identified by UniProt accession
Q96CP2, 140 residues long.
MolForge cross-references it against 0 known binders and
53 disease associations.
Target properties
| Protein name | FLYWCH family member 2 |
|---|
| UniProt accession | Q96CP2 |
|---|
| Gene | FLYWCH2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 140 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (53)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- Brugada syndrome · score 0.09
- familial atrial fibrillation · score 0.08
- Romano-Ward syndrome · score 0.08
- Familial short QT syndrome · score 0.07
- Familial progressive cardiac conduction defect · score 0.07
- Brugada syndrome 9 · score 0.07
- Arrhythmogenic right ventricular dysplasia · score 0.07
- familial sick sinus syndrome · score 0.06
- long QT syndrome 11 · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96CP2-F1 | alphafold | PREDICTED | 66.78 | — |
Amino-acid sequence (140 residues)
MPLPEPSEQE GESVKASQEP SPKPGTEVIP AAPRKPRKFS KLVLLTASKD STKVAGAKRK GVHCVMSLGV PGPATLAKAL LQTHPEAQRA IEAAPQEPEQ KRSRQDPGTD RTEDSGLAAG PPEAAGENFA PCSVAPGKSL
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