About TLC domain-containing protein 1
TLC domain-containing protein 1 (TLCD1) is a protein
from Homo sapiens identified by UniProt accession
Q96CP7, 247 residues long.
MolForge cross-references it against 0 known binders and
54 disease associations.
Target properties
| Protein name | TLC domain-containing protein 1 |
|---|
| UniProt accession | Q96CP7 |
|---|
| Gene | TLCD1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 247 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (54)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.13
- mean platelet volume · score 0.10
- urate measurement · score 0.08
- cancer · score 0.08
- platelet count · score 0.07
- apolipoprotein B measurement · score 0.06
- neoplasm · score 0.06
- reticulocyte measurement · score 0.05
- body height · score 0.05
- mean corpuscular hemoglobin concentration · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96CP7-F1 | alphafold | PREDICTED | 90.35 | — |
Amino-acid sequence (247 residues)
MPRLLHPALP LLLGATLTFR ALRRALCRLP LPVHVRADPL RTWRWHNLLV SFAHSIVSGI WALLCVWQTP DMLVEIETAW SLSGYLLVCF SAGYFIHDTV DIVASGQTRA SWEYLVHHVM AMGAFFSGIF WSSFVGGGVL TLLVEVSNIF LTIRMMMKIS NAQDHLLYRV NKYVNLVMYF LFRLAPQAYL THFFLRYVNQ RTLGTFLLGI LLMLDVMIII YFSRLLRSDF CPEHVPKKQH KDKFLTE
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