HAUS augmin-like complex subunit 1 (HAUS1)

About HAUS augmin-like complex subunit 1

HAUS augmin-like complex subunit 1 (HAUS1) is a protein from Homo sapiens identified by UniProt accession Q96CS2, 278 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.

Target properties

Protein name	HAUS augmin-like complex subunit 1
UniProt accession	Q96CS2
Gene	HAUS1
Organism	Homo sapiens
Length	278 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (35)

Diseases linked to this target (Open Targets).

ovarian cancer · score 0.23
breast adenocarcinoma · score 0.23
mean corpuscular volume · score 0.14
reticulocyte count · score 0.13
Red cell distribution width · score 0.11
mean reticulocyte volume · score 0.10
erythrocyte count · score 0.10
Immature Reticulocyte Fraction Measurement · score 0.10
mean corpuscular hemoglobin concentration · score 0.10
mean corpuscular hemoglobin · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96CS2-F1	alphafold	PREDICTED	88.61	—

Amino-acid sequence (278 residues)

MEPQEERETQ VAAWLKKIFG DHPIPQYEVN PRTTEILHHL SERNRVRDRD VYLVIEDLKQ KASEYESEAK YLQDLLMESV NFSPANLSST GSRYLNALVD SAVALETKDT SLASFIPAVN DLTSDLFRTK SKSEEIKIEL EKLEKNLTAT LVLEKCLQED VKKAELHLST ERAKVDNRRQ NMDFLKAKSE EFRFGIKAAE EQLSARGMDA SLSHQSLVAL SEKLARLKQQ TIPLKKKLES YLDLMPNPSL AQVKIEEAKR ELDSIEAELT RRVDMMEL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards