About DNA damage-inducible transcript 4-like protein
DNA damage-inducible transcript 4-like protein (DDIT4L) is a protein
from Homo sapiens identified by UniProt accession
Q96D03, 193 residues long.
MolForge cross-references it against 0 known binders and
66 disease associations.
Target properties
| Protein name | DNA damage-inducible transcript 4-like protein |
|---|
| UniProt accession | Q96D03 |
|---|
| Gene | DDIT4L |
|---|
| Organism | Homo sapiens |
|---|
| Length | 193 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (66)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.48
- FEV/FVC ratio · score 0.41
- creatinine measurement · score 0.41
- urate measurement · score 0.33
- mean platelet volume · score 0.33
- gut microbiome measurement · score 0.32
- mean corpuscular volume · score 0.31
- uric acid measurement · score 0.30
- mean reticulocyte volume · score 0.28
- glomerular filtration rate · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96D03-F1 | alphafold | PREDICTED | 76.95 | — |
Amino-acid sequence (193 residues)
MVATGSLSSK NPASISELLD CGYHPESLLS DFDYWDYVVP EPNLNEVIFE ESTCQNLVKM LENCLSKSKQ TKLGCSKVLV PEKLTQRIAQ DVLRLSSTEP CGLRGCVMHV NLEIENVCKK LDRIVCDSSV VPTFELTLVF KQENCSWTSF RDFFFSRGRF SSGFRRTLIL SSGFRLVKKK LYSLIGTTVI EGS
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