About GTP-binding protein Rhes
GTP-binding protein Rhes (RASD2) is a protein
from Homo sapiens identified by UniProt accession
Q96D21, 266 residues long.
MolForge cross-references it against 0 known binders and
49 disease associations.
Target properties
| Protein name | GTP-binding protein Rhes |
|---|
| UniProt accession | Q96D21 |
|---|
| Gene | RASD2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 266 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (49)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.36
- intelligence · score 0.30
- balding measurement · score 0.23
- Huntington disease · score 0.09
- schizophrenia · score 0.05
- Barrett's esophagus · score 0.04
- triglyceride measurement · score 0.03
- cutaneous melanoma · score 0.03
- Parkinson disease · score 0.02
- tauopathy · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96D21-F1 | alphafold | PREDICTED | 83.03 | — |
Amino-acid sequence (266 residues)
MMKTLSSGNC TLSVPAKNSY RMVVLGASRV GKSSIVSRFL NGRFEDQYTP TIEDFHRKVY NIRGDMYQLD ILDTSGNHPF PAMRRLSILT GDVFILVFSL DNRESFDEVK RLQKQILEVK SCLKNKTKEA AELPMVICGN KNDHGELCRQ VPTTEAELLV SGDENCAYFE VSAKKNTNVD EMFYVLFSMA KLPHEMSPAL HRKISVQYGD AFHPRPFCMR RVKEMDAYGM VSPFARRPSV NSDLKYIKAK VLREGQARER DKCTIQ
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