About R3H domain-containing protein 4
R3H domain-containing protein 4 (R3HDM4) is a protein
from Homo sapiens identified by UniProt accession
Q96D70, 268 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | R3H domain-containing protein 4 |
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| UniProt accession | Q96D70 |
|---|
| Gene | R3HDM4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 268 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- reticulocyte measurement · score 0.64
- reticulocyte count · score 0.62
- Immature Reticulocyte Fraction Measurement · score 0.53
- neurodegenerative disease · score 0.48
- platelet count · score 0.08
- platelet component distribution width · score 0.03
- Crohn's disease · score 0.00
- type 1 diabetes mellitus · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96D70-F1 | alphafold | PREDICTED | 76.02 | — |
Amino-acid sequence (268 residues)
MVALENPECG PEAAEGTPGG RRLLPLPSCL PALASSQVKR LSASRRKQHF INQAVRNSDL VPKAKGRKSL QRLENTQYLL TLLETDGGLP GLEDGDLAPP ASPGIFAEAC NNATYVEVWN DFMNRSGEEQ ERVLRYLEDE GRSKARRRGP GRGEDRRRED PAYTPRECFQ RISRRLRAVL KRSRIPMETL ETWEERLLRF FSVSPQAVYT AMLDNSFERL LLHAVCQYMD LISASADLEG KRQMKVSNRH LDFLPPGLLL SAYLEQHS
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