About EP300-interacting inhibitor of differentiation 2B
EP300-interacting inhibitor of differentiation 2B (EID2B) is a protein
from Homo sapiens identified by UniProt accession
Q96D98, 161 residues long.
MolForge cross-references it against 0 known binders and
17 disease associations.
Target properties
| Protein name | EP300-interacting inhibitor of differentiation 2B |
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| UniProt accession | Q96D98 |
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| Gene | EID2B |
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| Organism | Homo sapiens |
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| Length | 161 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (17)
Diseases linked to this target (Open Targets).
- genetic disorder · score 0.12
- dehydrated hereditary stomatocytosis · score 0.04
- diabetes mellitus, permanent neonatal 4 · score 0.04
- MODY · score 0.04
- diabetes mellitus, transient neonatal, 3 · score 0.04
- ghosal hematodiaphyseal dysplasia · score 0.03
- permanent neonatal diabetes mellitus 1 · score 0.03
- 22q11.2 deletion syndrome · score 0.03
- familial pseudohyperkalemia · score 0.03
- autosomal recessive hypophosphatemic rickets · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96D98-F1 | alphafold | PREDICTED | 68.57 | — |
Amino-acid sequence (161 residues)
MAEPTGLLEM SELPGDSSVP QVGTASGVSD VLRGAVGGGV RVQEAREGPV AEAARSMARM PGPVPGPIPS SVPGLASAPD PHQQLAFLEI NRQLLFREYL DGSSMIPVRL LRDFEERRRL FVEGCKAREA AFDADPPQMD FAAVAFTVAL TASEALSPLA D
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