Pancreatic adenocarcinoma up-regulated factor (ZG16B)

About Pancreatic adenocarcinoma up-regulated factor

Pancreatic adenocarcinoma up-regulated factor (ZG16B) is a protein from Homo sapiens identified by UniProt accession Q96DA0, 172 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.

Target properties

Protein name	Pancreatic adenocarcinoma up-regulated factor
UniProt accession	Q96DA0
Gene	ZG16B
Organism	Homo sapiens
Length	172 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (54)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.25
Barrett's esophagus · score 0.04
pancreatic neoplasm · score 0.03
cancer · score 0.03
neoplasm · score 0.02
ulcerative colitis · score 0.02
Crohn's disease · score 0.02
COVID-19 · score 0.01
atherosclerosis · score 0.01
pancreatic carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96DA0-F1	alphafold	PREDICTED	87.45	—

Amino-acid sequence (172 residues)

MLLLLTLALL GGPTWAGKMY GPGGGKYFST TEDYDHEITG LRVSVGLLLV KSVQVKLGDS WDVKLGALGG NTQEVTLQPG EYITKVFVAF QAFLRGMVMY TSKDRYFYFG KLDGQISSAY PSQEGQVLVG IYGQYQLLGI KSIGFEWNYP LEEPTTEPPV NLTYSANSPV GR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards