Splicing factor ESS-2 homolog (ESS2)

Homo sapiens — UniProt Q96DF8

Gene: ESS2Homo sapiensSwissProt reviewed

About Splicing factor ESS-2 homolog

Splicing factor ESS-2 homolog (ESS2) is a protein from Homo sapiens identified by UniProt accession Q96DF8, 476 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

Target properties

Protein nameSplicing factor ESS-2 homolog
UniProt accessionQ96DF8
GeneESS2
OrganismHomo sapiens
Length476 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q96DF8-F1alphafoldPREDICTED67.27—

Amino-acid sequence (476 residues)

METPGASASS LLLPAASRPP RKREAGEAGA ATSKQRVLDE EEYIEGLQTV IQRDFFPDVE KLQAQKEYLE AEENGDLERM RQIAIKFGSA LGKMSREPPP PYVTPATFET PEVHAGTGVV GNKPRPRGRG LEDGEAGEEE EKEPLPSLDV FLSRYTSEDN ASFQEIMEVA KERSRARHAW LYQAEEEFEK RQKDNLELPS AEHQAIESSQ ASVETWKYKA KNSLMYYPEG VPDEEQLFKK PRQVVHKNTR FLRDPFSQAL SRCQLQQAAA LNAQHKQGKV GPDGKELIPQ ESPRVGGFGF VATPSPAPGV NESPMMTWGE VENTPLRVEG SETPYVDRTP GPAFKILEPG RRERLGLKMA NEAAAKNRAK KQEALRRVTE NLASLTPKGL SPAMSPALQR LVSRTASKYT DRALRASYTP SPARSTHLKT PASGLQTPTS TPAPGSATRT PLTQDPASIT DNLLQLPARR KASDFF

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Quick facts

UniProtQ96DF8
GeneESS2
OrganismHomo sapiens
Length476
Binders0
Diseases19
View on UniProt