PiggyBac transposable element-derived protein 4 (PGBD4)

Homo sapiens — UniProt Q96DM1

Gene: PGBD4Homo sapiensSwissProt reviewed

About PiggyBac transposable element-derived protein 4

PiggyBac transposable element-derived protein 4 (PGBD4) is a protein from Homo sapiens identified by UniProt accession Q96DM1, 585 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.

Target properties

Protein namePiggyBac transposable element-derived protein 4
UniProt accessionQ96DM1
GenePGBD4
OrganismHomo sapiens
Length585 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (2)

Diseases linked to this target (Open Targets).

  • genetic disorder · score 0.12
  • protein measurement · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q96DM1-F1alphafoldPREDICTED82.84—

Amino-acid sequence (585 residues)

MSNPRKRSIP MRDSNTGLEQ LLAEDSFDES DFSEIDDSDN FSDSALEADK IRPLSHLESD GKSSTSSDSG RSMKWSARAM IPRQRYDFTG TPGRKVDVSD ITDPLQYFEL FFTEELVSKI TRETNAQAAL LASKPPGPKG FSRMDKWKDT DNDELKVFFA VMLLQGIVQK PELEMFWSTR PLLDTPYLRQ IMTGERFLLL FRCLHFVNNS SISAGQSKAQ ISLQKIKPVF DFLVNKFSTV YTPNRNIAVD ESLMLFKGPL AMKQYLPTKR VRFGLKLYVL CESQSGYVWN ALVHTGPGMN LKDSADGLKS SRIVLTLVND LLGQGYCVFL DNFNISPMLF RELHQNRTDA VGTARLNRKQ IPNDLKKRIA KGTTVARFCG ELMALKWCDG KEVTMLSTFH NDTVIEVNNR NGKKTKRPRV IVDYNENMGA VDSADQMLTS YPSERKRHKV WYKKFFHHLL HITVLNSYIL FKKDNPEHTM SHINFRLALI ERMLEKHHKP GQQHLRGRPC SDDVTPLRLS GRHFPKSIPA TSGKQNPTGR CKICCSQYDK DGKKIRKETR YFCAECDVPL CVVPCFEIYH TKKNY

Explore PiggyBac transposable element-derived protein 4 with MolForge

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Quick facts

UniProtQ96DM1
GenePGBD4
OrganismHomo sapiens
Length585
Binders0
Diseases2
View on UniProt