About von Willebrand factor C and EGF domain-containing protein
von Willebrand factor C and EGF domain-containing protein (VWCE) is a protein
from Homo sapiens identified by UniProt accession
Q96DN2, 955 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | von Willebrand factor C and EGF domain-containing protein |
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| UniProt accession | Q96DN2 |
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| Gene | VWCE |
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| Organism | Homo sapiens |
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| Length | 955 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96DN2-F1 | alphafold | PREDICTED | 62.70 | — |
Amino-acid sequence (955 residues)
MWAGLLLRAA CVALLLPGAP ARGYTGRKPP GHFAAERRRL GPHVCLSGFG SGCCPGWAPS MGGGHCTLPL CSFGCGSGIC IAPNVCSCQD GEQGATCPET HGPCGEYGCD LTCNHGGCQE VARVCPVGFS MTETAVGIRC TDIDECVTSS CEGHCVNTEG GFVCECGPGM QLSADRHSCQ DTDECLGTPC QQRCKNSIGS YKCSCRTGFH LHGNRHSCVD VNECRRPLER RVCHHSCHNT VGSFLCTCRP GFRLRADRVS CEAFPKAVLA PSAILQPRQH PSKMLLLLPE AGRPALSPGH SPPSGAPGPP AGVRTTRLPS PTPRLPTSSP SAPVWLLSTL LATPVPTASL LGNLRPPSLL QGEVMGTPSS PRGPESPRLA AGPSPCWHLG AMHESRSRWT EPGCSQCWCE DGKVTCEKVR CEAACSHPIP SRDGGCCPSC TGCFHSGVVR AEGDVFSPPN ENCTVCVCLA GNVSCISPEC PSGPCQTPPQ TDCCTCVPVR CYFHGRWYAD GAVFSGGGDE CTTCVCQNGE VECSFMPCPE LACPREEWRL GPGQCCFTCQ EPTPSTGCSL DDNGVEFPIG QIWSPGDPCE LCICQADGSV SCKRTDCVDS CPHPIRIPGQ CCPDCSAGCT YTGRIFYNNE TFPSVLDPCL SCICLLGSVA CSPVDCPITC TYPFHPDGEC CPVCRDCNYE GRKVANGQVF TLDDEPCTRC TCQLGEVSCE KVPCQRACAD PALLPGDCCS SCPDSLSPLE EKQGLSPHGN VAFSKAGRSL HGDTEAPVNC SSCPGPPTAS PSRPVLHLLQ LLLRTNLMKT QTLPTSPAGA HGPHSLALGL TATFPGEPGA SPRLSPGPST PPGAPTLPLA SPGAPQPPPV TPERSFSASG AQIVSRWPPL PGTLLTEASA LSMMDPSPSK TPITLLGPRV LSPTTSRLST ALAATTHPGP QQPPVGASRG EESTM
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