About Methyl-CpG-binding domain protein 6
Methyl-CpG-binding domain protein 6 (MBD6) is a protein
from Homo sapiens identified by UniProt accession
Q96DN6, 1003 residues long.
MolForge cross-references it against 0 known binders and
99 disease associations.
Target properties
| Protein name | Methyl-CpG-binding domain protein 6 |
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| UniProt accession | Q96DN6 |
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| Gene | MBD6 |
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| Organism | Homo sapiens |
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| Length | 1003 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96DN6-F1 | alphafold | PREDICTED | 43.23 | — |
Amino-acid sequence (1003 residues)
MNGGNESSGA DRAGGPVATS VPIGWQRCVR EGAVLYISPS GTELSSLEQT RSYLLSDGTC KCGLECPLNV PKVFNFDPLA PVTPGGAGVG PASEEDMTKL CNHRRKAVAM ATLYRSMETT CSHSSPGEGA SPQMFHTVSP GPPSARPPCR VPPTTPLNGG PGSLPPEPPS VSQAFPTLAG PGGLFPPRLA DPVPSGGSSS PRFLPRGNAP SPAPPPPPAI SLNAPSYNWG AALRSSLVPS DLGSPPAPHA SSSPPSDPPL FHCSDALTPP PLPPSNNLPA HPGPASQPPV SSATMHLPLV LGPLGGAPTV EGPGAPPFLA SSLLSAAAKA QHPPLPPPST LQGRRPRAQA PSASHSSSLR PSQRRPRRPP TVFRLLEGRG PQTPRRSRPR APAPVPQPFS LPEPSQPILP SVLSLLGLPT PGPSHSDGSF NLLGSDAHLP PPPTLSSGSP PQPRHPIQPS LPGTTSGSLS SVPGAPAPPA ASKAPVVPSP VLQSPSEGLG MGAGPACPLP PLAGGEAFPF PSPEQGLALS GAGFPGMLGA LPLPLSLGQP PPSPLLNHSL FGVLTGGGGQ PPPEPLLPPP GGPGPPLAPG EPEGPSLLVA SLLPPPPSDL LPPPSAPPSN LLASFLPLLA LGPTAGDGEG SAEGAGGPSG EPFSGLGDLS PLLFPPLSAP PTLIALNSAL LAATLDPPSG TPPQPCVLSA PQPGPPTSSV TTATTDPGAS SLGKAPSNSG RPPQLLSPLL GASLLGDLSS LTSSPGALPS LLQPPGPLLS GQLGLQLLPG GGAPPPLSEA SSPLACLLQS LQIPPEQPEA PCLPPESPAS ALEPEPARPP LSALAPPHGS PDPPVPELLT GRGSGKRGRR GGGGLRGING EARPARGRKP GSRREPGRLA LKWGTRGGFN GQMERSPRRT HHWQHNGELA EGGAEPKDPP PPGPHSEDLK VPPGVVRKSR RGRRRKYNPT RNSNSSRQDI TLEPSPTARA AVPLPPRARP GRPAKNKRRK LAP
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