StAR-related lipid transfer protein 4 (STARD4)

Homo sapiens — UniProt Q96DR4

Gene: STARD4Homo sapiensSwissProt reviewed

About StAR-related lipid transfer protein 4

StAR-related lipid transfer protein 4 (STARD4) is a protein from Homo sapiens identified by UniProt accession Q96DR4, 205 residues long. MolForge cross-references it against 0 known binders and 82 disease associations.

Target properties

Protein nameStAR-related lipid transfer protein 4
UniProt accessionQ96DR4
GeneSTARD4
OrganismHomo sapiens
Length205 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (82)

Diseases linked to this target (Open Targets).

  • age at menarche · score 0.39
  • body height · score 0.29
  • ovarian cancer · score 0.18
  • monocyte count · score 0.18
  • arterial stiffness measurement · score 0.18
  • squamous cell lung carcinoma · score 0.16
  • leukocyte count · score 0.14
  • cognitive function measurement · score 0.13
  • PR interval · score 0.13
  • myeloid white cell count · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q96DR4-F1alphafoldPREDICTED95.90—

Amino-acid sequence (205 residues)

MEGLSDVASF ATKLKNTLIQ YHSIEEDKWR VAKKTKDVTV WRKPSEEFNG YLYKAQGVID DLVYSIIDHI RPGPCRLDWD SLMTSLDILE NFEENCCVMR YTTAGQLWNI ISPREFVDFS YTVGYKEGLL SCGISLDWDE KRPEFVRGYN HPCGWFCVPL KDNPNQSLLT GYIQTDLRGM IPQSAVDTAM ASTLTNFYGD LRKAL

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Quick facts

UniProtQ96DR4
GeneSTARD4
OrganismHomo sapiens
Length205
Binders0
Diseases82
View on UniProt