About BPI fold-containing family A member 2
BPI fold-containing family A member 2 (BPIFA2) is a protein
from Homo sapiens identified by UniProt accession
Q96DR5, 249 residues long.
MolForge cross-references it against 0 known binders and
37 disease associations.
Target properties
| Protein name | BPI fold-containing family A member 2 |
|---|
| UniProt accession | Q96DR5 |
|---|
| Gene | BPIFA2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 249 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (37)
Diseases linked to this target (Open Targets).
- lung adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- glioblastoma multiforme · score 0.17
- endometrial cancer · score 0.15
- breast adenocarcinoma · score 0.10
- non-small cell lung carcinoma · score 0.03
- dry eye syndrome · score 0.02
- Systemic lupus erythematosus · score 0.02
- mixed connective tissue disease · score 0.02
- systemic scleroderma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96DR5-F1 | alphafold | PREDICTED | 65.67 | — |
Amino-acid sequence (249 residues)
MLQLWKLVLL CGVLTGTSES LLDNLGNDLS NVVDKLEPVL HEGLETVDNT LKGILEKLKV DLGVLQKSSA WQLAKQKAQE AEKLLNNVIS KLLPTNTDIF GLKISNSLIL DVKAEPIDDG KGLNLSFPVT ANVTVAGPII GQIINLKASL DLLTAVTIET DPQTHQPVAV LGECASDPTS ISLSLLDKHS QIINKFVNSV INTLKSTVSS LLQKEICPLI RIFIHSLDVN VIQQVVDNPQ HKTQLQTLI
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