About Zinc finger and BTB domain-containing protein 10
Zinc finger and BTB domain-containing protein 10 (ZBTB10) is a protein
from Homo sapiens identified by UniProt accession
Q96DT7, 871 residues long.
MolForge cross-references it against 0 known binders and
91 disease associations.
Target properties
| Protein name | Zinc finger and BTB domain-containing protein 10 |
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| UniProt accession | Q96DT7 |
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| Gene | ZBTB10 |
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| Organism | Homo sapiens |
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| Length | 871 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (91)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.52
- testosterone measurement · score 0.48
- systolic blood pressure · score 0.47
- hemoglobin measurement · score 0.47
- asthma · score 0.46
- hematocrit · score 0.45
- diastolic blood pressure · score 0.45
- mean platelet volume · score 0.45
- neurodegenerative disease · score 0.44
- body mass index · score 0.43
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96DT7-F1 | alphafold | PREDICTED | 48.89 | — |
Amino-acid sequence (871 residues)
MSFSEMNRRT LAFRGGGLVT ASGGGSTNNN AGGEASAWPP QPQPRQPPPP APPALQPPNG RGADEEVELE GLEPQDLEAS AGPAAGAAEE AKELLLPQDA GGPTSLGGGA GGPLLAERNR RTLAFRGGGG GGLGNNGSSR GRPETSVWPL RHFNGRGPAT VDLELDALEG KELMQDGASL SDSTEDEEEG ASLGDGSGAE GGSCSSSRRS GGDGGDEVEG SGVGAGEGET VQHFPLARPK SLMQKLQCSF QTSWLKDFPW LRYSKDTGLM SCGWCQKTPA DGGSVDLPPV GHDELSRGTR NYKKTLLLRH HVSTEHKLHE ANAQESEIPS EEGYCDFNSR PNENSYCYQL LRQLNEQRKK GILCDVSIVV SGKIFKAHKN ILVAGSRFFK TLYCFSNKES PNQNNTTHLD IAAVQGFSVI LDFLYSGNLV LTSQNAIEVM TVASYLQMSE VVQTCRNFIK DALNISIKSE APESVVVDYN NRKPVNRDGL SSSRDQKIAS FWATRNLTNL ASNVKIENDG CNVDEGQIEN YQMNDSSWVQ DGSPEMAENE SEGQTKVFIW NNMGSQGIQE TGKTRRKNQT TKRFIYNIPP NNETNLEDCS VMQPPVAYPE ENTLLIKEEP DLDGALLSGP DGDRNVNANL LAEAGTSQDG GDAGTSHDFK YGLMPGPSND FKYGLIPGTS NDFKYGLIPG ASNDFKYGLL PESWPKQETW ENGESSLIMN KLKCPHCSYV AKYRRTLKRH LLIHTGVRSF SCDICGKLFT RREHVKRHSL VHKKDKKYKC MVCKKIFMLA ASVGIRHGSR RYGVCVDCAD KSQPGGQEGV DQGQDTEFPR DEEYEENEVG EADEELVDDG EDQNDPSRWD ESGEVCMSLD D
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