Ankyrin repeat and SOCS box protein 9 (ASB9)

About Ankyrin repeat and SOCS box protein 9

Ankyrin repeat and SOCS box protein 9 (ASB9) is a protein from Homo sapiens identified by UniProt accession Q96DX5, 294 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	Ankyrin repeat and SOCS box protein 9
UniProt accession	Q96DX5
Gene	ASB9
Organism	Homo sapiens
Length	294 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

3-hydroxy-1-methylpropylmercapturic acid measurement · score 0.31
clear cell renal carcinoma · score 0.02
hepatocellular carcinoma · score 0.01
colorectal cancer · score 0.01
extranodal nasal NK/T cell lymphoma · score 0.01
liver hemangioma · score 0.01
Azoospermia · score 0.01
ulnar-mammary syndrome · score 0.01
psoriasis · score 0.01
gonorrhea · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96DX5-F1	alphafold	PREDICTED	91.51	—

Amino-acid sequence (294 residues)

MDGKQGGMDG SKPAGPRDFP GIRLLSNPLM GDAVSDWSPM HEAAIHGHQL SLRNLISQGW AVNIITADHV SPLHEACLGG HLSCVKILLK HGAQVNGVTA DWHTPLFNAC VSGSWDCVNL LLQHGASVQP ESDLASPIHE AARRGHVECV NSLIAYGGNI DHKISHLGTP LYLACENQQR ACVKKLLESG ADVNQGKGQD SPLHAVARTA SEELACLLMD FGADTQAKNA EGKRPVELVP PESPLAQLFL EREGPPSLMQ LCRLRIRKCF GIQQHHKITK LVLPEDLKQF LLHL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards