Receptor-transporting protein 4 (RTP4)

About Receptor-transporting protein 4

Receptor-transporting protein 4 (RTP4) is a protein from Homo sapiens identified by UniProt accession Q96DX8, 246 residues long. MolForge cross-references it against 0 known binders and 81 disease associations.

Target properties

Protein name	Receptor-transporting protein 4
UniProt accession	Q96DX8
Gene	RTP4
Organism	Homo sapiens
Length	246 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (81)

Diseases linked to this target (Open Targets).

attention deficit hyperactivity disorder · score 0.07
schizophrenia 15 · score 0.06
Tourette syndrome · score 0.05
attention deficit-hyperactivity disorder 8 · score 0.05
Phelan-McDermid syndrome · score 0.05
thrombocytopenia 4 · score 0.04
platelet-type bleeding disorder 15 · score 0.04
macrothrombocytopenia, isolated, 2, autosomal dominant · score 0.04
bleeding disorder, platelet-type, 24 · score 0.04
thrombocytopenia 2 · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96DX8-F1	alphafold	PREDICTED	78.23	—

Amino-acid sequence (246 residues)

MVVDFWTWEQ TFQELIQEAK PRATWTLKLD GNLQLDCLAQ GWKQYQQRAF GWFRCSSCQR SWASAQVQIL CHTYWEHWTS QGQVRMRLFG QRCQKCSWSQ YEMPEFSSDS TMRILSNLVQ HILKKYYGNG TRKSPEMPVI LEVSLEGSHD TANCEACTLG ICGQGLKSCM TKPSKSLLPH LKTGNSSPGI GAVYLANQAK NQSAEAKEAK GSGYEKLGPS RDPDPLNICV FILLLVFIVV KCFTSE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards