Small integral membrane protein 19 (SMIM19)

About Small integral membrane protein 19

Small integral membrane protein 19 (SMIM19) is a protein from Homo sapiens identified by UniProt accession Q96E16, 107 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.

Target properties

Protein name	Small integral membrane protein 19
UniProt accession	Q96E16
Gene	SMIM19
Organism	Homo sapiens
Length	107 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (40)

Diseases linked to this target (Open Targets).

mean corpuscular hemoglobin concentration · score 0.36
mean corpuscular volume · score 0.34
self reported educational attainment · score 0.29
Red cell distribution width · score 0.29
neurodegenerative disease · score 0.29
red blood cell density measurement · score 0.28
erythrocyte count · score 0.28
hemoglobin measurement · score 0.27
bilirubin measurement · score 0.26
body height · score 0.25

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96E16-F1	alphafold	PREDICTED	67.51	—

Amino-acid sequence (107 residues)

MAGGYGVMGD DGSIDYTVHE AWNEATNVYL IVILVSFGLF MYAKRNKRRI MRIFSVPPTE ETLSEPNFYD TISKIRLRQQ LEMYSISRKY DYQQPQNQAD SVQLSLE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards