About Killer cell lectin-like receptor subfamily G member 1
Killer cell lectin-like receptor subfamily G member 1 (KLRG1) is a protein
from Homo sapiens identified by UniProt accession
Q96E93, 195 residues long.
MolForge cross-references it against 0 known binders and
192 disease associations.
Target properties
| Protein name | Killer cell lectin-like receptor subfamily G member 1 |
|---|
| UniProt accession | Q96E93 |
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| Gene | KLRG1 |
|---|
| Organism | Homo sapiens |
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| Length | 195 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (192)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.39
- eosinophil count · score 0.37
- type 1 diabetes mellitus · score 0.35
- appendicular lean mass · score 0.35
- total cholesterol measurement · score 0.34
- fat body mass · score 0.32
- red blood cell density measurement · score 0.28
- low density lipoprotein cholesterol measurement · score 0.28
- body height · score 0.25
- whole body water mass · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96E93-F1 | alphafold | PREDICTED | 81.35 | — |
Amino-acid sequence (195 residues)
MTDSVIYSML ELPTATQAQN DYGPQQKSSS SRPSCSCLVA IALGLLTAVL LSVLLYQWIL CQGSNYSTCA SCPSCPDRWM KYGNHCYYFS VEEKDWNSSL EFCLARDSHL LVITDNQEMS LLQVFLSEAF CWIGLRNNSG WRWEDGSPLN FSRISSNSFV QTCGAINKNG LQASSCEVPL HWVCKKCPFA DQALF
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