About Nucleoporin SEH1
Nucleoporin SEH1 (SEH1L) is a protein
from Homo sapiens identified by UniProt accession
Q96EE3, 360 residues long.
MolForge cross-references it against 0 known binders and
84 disease associations.
Target properties
| Protein name | Nucleoporin SEH1 |
|---|
| UniProt accession | Q96EE3 |
|---|
| Gene | SEH1L |
|---|
| Organism | Homo sapiens |
|---|
| Length | 360 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (84)
Diseases linked to this target (Open Targets).
- HIV infection · score 0.54
- influenza · score 0.54
- viral disease · score 0.53
- COVID-19 · score 0.37
- Histiocytosis · score 0.37
- neurodegenerative disease · score 0.35
- Alzheimer disease · score 0.29
- multiple sclerosis · score 0.29
- lysosomal storage disease · score 0.29
- Parkinson disease · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96EE3-F1 | alphafold | PREDICTED | 86.91 | — |
Amino-acid sequence (360 residues)
MFVARSIAAD HKDLIHDVSF DFHGRRMATC SSDQSVKVWD KSESGDWHCT ASWKTHSGSV WRVTWAHPEF GQVLASCSFD RTAAVWEEIV GESNDKLRGQ SHWVKRTTLV DSRTSVTDVK FAPKHMGLML ATCSADGIVR IYEAPDVMNL SQWSLQHEIS CKLSCSCISW NPSSSRAHSP MIAVGSDDSS PNAMAKVQIF EYNENTRKYA KAETLMTVTD PVHDIAFAPN LGRSFHILAI ATKDVRIFTL KPVRKELTSS GGPTKFEIHI VAQFDNHNSQ VWRVSWNITG TVLASSGDDG CVRLWKANYM DNWKCTGILK GNGSPVNGSS QQGTSNPSLG STIPSLQNSL NGSSAGRKHS
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