About Zinc finger protein 837
Zinc finger protein 837 (ZNF837) is a protein
from Homo sapiens identified by UniProt accession
Q96EG3, 531 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Zinc finger protein 837 |
|---|
| UniProt accession | Q96EG3 |
|---|
| Gene | ZNF837 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 531 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (9)
Diseases linked to this target (Open Targets).
- multiple sclerosis · score 0.26
- neurodegenerative disease · score 0.26
- lysosomal storage disease · score 0.26
- Alzheimer disease · score 0.26
- Parkinson disease · score 0.26
- platelet component distribution width · score 0.03
- platelet count · score 0.02
- COVID-19 · score 0.01
- Dravet syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96EG3-F1 | alphafold | PREDICTED | 58.15 | — |
Amino-acid sequence (531 residues)
MEAPAQKAGQ GGLPKADAQG ASGAREKRPE EPRPLEEDRA GSRPTQKGDL RGAAGGRTTP PGGGSRGCSL GVSPGPGTRH SAGTRPLVRE PCGPTSSQNP ELVIPEGLQA REGPCRSPAR GGDCSRNSCL AWHRGAPAGE TPPVCDPCPE RIQNHPRTQL CEVHTDCWPC QPGTGAPTCP RTPKPTSRGR NPLVEQPRAC ACGEAFAWRA LRIPQERLQA TEEPRPCARC GKRFRPNQQQ QAGKSPPVCP ECGQTSRPRP IVPDPPAQRL YACDECGKAF TRTSSLLQHQ RIHTGERPYE CAECGKAFVR CSGLYRHQKT HSAERHRRGP VLARRAFRLG CPPCGDYSER SPRRGSGAGE KPYECADCAK AFGLFSHLVE HRRVHTGEKP YACPECGKAF NQRSNLSRHQ RTHSSAKPYA CPLCEKAFKG RSGLVQHQRA HTGERPYGCS ECGKTFRGCS ELRQHERLHS GEKPYICRDC GKAFVRNCSL VRHLRTHTGE RPYACGDCGR AFSQRSNLNE HRKRHGGRAA P
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