Putative sodium/bile acid cotransporter 4 (SLC10A4)

About Putative sodium/bile acid cotransporter 4

Putative sodium/bile acid cotransporter 4 (SLC10A4) is a protein from Homo sapiens identified by UniProt accession Q96EP9, 437 residues long. MolForge cross-references it against 0 known binders and 99 disease associations.

Target properties

Protein name	Putative sodium/bile acid cotransporter 4
UniProt accession	Q96EP9
Gene	SLC10A4
Organism	Homo sapiens
Length	437 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (99)

Diseases linked to this target (Open Targets).

body height · score 0.15
hematocrit · score 0.14
hemoglobin measurement · score 0.14
age at menopause · score 0.11
systolic blood pressure · score 0.11
cortical surface area measurement · score 0.11
X-linked non-syndromic intellectual disability · score 0.10
pulse pressure measurement · score 0.09
sitting height measurement · score 0.09
brain measurement · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96EP9-F1	alphafold	PREDICTED	70.87	—

Amino-acid sequence (437 residues)

MDGNDNVTLL FAPLLRDNYT LAPNASSLGP GTDLALAPAS SAGPGPGLSL GPGPSFGFSP GPTPTPEPTT SGLAGGAASH GPSPFPRPWA PHALPFWDTP LNHGLNVFVG AALCITMLGL GCTVDVNHFG AHVRRPVGAL LAALCQFGLL PLLAFLLALA FKLDEVAAVA VLLCGCCPGG NLSNLMSLLV DGDMNLSIIM TISSTLLALV LMPLCLWIYS WAWINTPIVQ LLPLGTVTLT LCSTLIPIGL GVFIRYKYSR VADYIVKVSL WSLLVTLVVL FIMTGTMLGP ELLASIPAAV YVIAIFMPLA GYASGYGLAT LFHLPPNCKR TVCLETGSQN VQLCTAILKL AFPPQFIGSM YMFPLLYALF QSAEAGIFVL IYKMYGSEML HKRDPLDEDE DTDISYKKLK EEEMADTSYG TVKAENIIMM ETAQTSL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards