About Golgi apparatus membrane protein TVP23 homolog C
Golgi apparatus membrane protein TVP23 homolog C (TVP23C) is a protein
from Homo sapiens identified by UniProt accession
Q96ET8, 276 residues long.
MolForge cross-references it against 0 known binders and
49 disease associations.
Target properties
| Protein name | Golgi apparatus membrane protein TVP23 homolog C |
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| UniProt accession | Q96ET8 |
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| Gene | TVP23C |
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| Organism | Homo sapiens |
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| Length | 276 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (49)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- diet measurement · score 0.26
- diastolic blood pressure · score 0.12
- resting heart rate · score 0.11
- inflammatory bowel disease · score 0.07
- Autosomal recessive early-onset inflammatory bowel disease · score 0.06
- inflammatory bowel disease 30 · score 0.06
- inflammatory bowel disease 1 · score 0.06
- ulcerative colitis · score 0.06
- Crohn's disease · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96ET8-F1 | alphafold | PREDICTED | 59.00 | — |
Amino-acid sequence (276 residues)
MLQQDSNDDT EDVSLFDAEE ETTNRPRKAK IRHPVASFFH LFFRVSAIIV CLLCELLSSS FITCMVTIIL LLSCDFWAVK NVTGRLMVGL RWWNHIDEDG KSHWVFESRK ESSQENKTVS EAESRIFWLG LIACSVLWVI FAFSALFSFT VKWLRRSRHI AQTGLKVLGS RDPPASAFQS AGITGVSRCP GHPSRKFHQV DINSFTRITD RALYWKPAPR LSSPPLRAAP GNCQQMAPAR LFLSLRLWAW RGGGESPNSR GTGEPGPKFH LASGMH
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