About Dysbindin
Dysbindin (DTNBP1) is a protein
from Homo sapiens identified by UniProt accession
Q96EV8, 351 residues long.
MolForge cross-references it against 0 known binders and
199 disease associations.
Target properties
| Protein name | Dysbindin |
|---|
| UniProt accession | Q96EV8 |
|---|
| Gene | DTNBP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 351 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (199)
Diseases linked to this target (Open Targets).
- Hermansky-Pudlak syndrome 7 · score 0.68
- Hermansky-Pudlak syndrome · score 0.57
- Hermansky-Pudlak syndrome type 7 · score 0.48
- alkaline phosphatase measurement · score 0.42
- body height · score 0.24
- appendicular lean mass · score 0.21
- squamous cell carcinoma · score 0.19
- genetic disorder · score 0.19
- blood protein measurement · score 0.18
- refractive error measurement · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96EV8-F1 | alphafold | PREDICTED | 74.85 | — |
Amino-acid sequence (351 residues)
MLETLRERLL SVQQDFTSGL KTLSDKSREA KVKSKPRTVP FLPKYSAGLE LLSRYEDTWA ALHRRAKDCA SAGELVDSEV VMLSAHWEKK KTSLVELQEQ LQQLPALIAD LESMTANLTH LEASFEEVEN NLLHLEDLCG QCELERCKHM QSQQLENYKK NKRKELETFK AELDAEHAQK VLEMEHTQQM KLKERQKFFE EAFQQDMEQY LSTGYLQIAE RREPIGSMSS MEVNVDMLEQ MDLMDISDQE ALDVFLNSGG EENTVLSPAL GPESSTCQNE ITLQVPNPSE LRAKPPSSSS TCTDSATRDI SEGGESPVVQ SDEEEVQVDT ALATSHTDRE ATPDGGEDSD S
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