HSPB1-associated protein 1 (HSPBAP1)

About HSPB1-associated protein 1

HSPB1-associated protein 1 (HSPBAP1) is a protein from Homo sapiens identified by UniProt accession Q96EW2, 488 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.

Target properties

Protein name	HSPB1-associated protein 1
UniProt accession	Q96EW2
Gene	HSPBAP1
Organism	Homo sapiens
Length	488 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (22)

Diseases linked to this target (Open Targets).

hair color · score 0.21
serum gamma-glutamyl transferase measurement · score 0.21
serum albumin measurement · score 0.17
mean platelet volume · score 0.14
hair colour measurement · score 0.09
calcium measurement · score 0.04
protein measurement · score 0.04
infection · score 0.02
infect · score 0.02
neoplasm · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96EW2-F1	alphafold	PREDICTED	78.51	—

Amino-acid sequence (488 residues)

MAAGSEATTP VIVAAGAGGE EGEHVKPFKP EKAKEIIMSL QQPAIFCNMV FDWPARHWNA KYLSQVLHGK QIRFRMGMKS MSTVPQFETT CNYVEATLEE FLTWNCDQSS ISGPFRDYDH SKFWAYADYK YFVSLFEDKT DLFQDVKWSD FGFPGRNGQE STLWIGSLGA HTPCHLDSYG CNLVFQVQGR KRWHLFPPED TPFLYPTRIP YEESSVFSKI NVVNPDLKRF PQFRKAQRHA VTLSPGQVLF VPRHWWHYVE SIDPVTVSIN SWIELEEDHL ARVEEAITRM LVCALKTAEN PQNTRAWLNP TEVEETSHAV NCCYLNAAVS AFFDRCRTSE VVEIQALRTD GEHMKKEELN VCNHMEVGQT GSQNLTTGTD KPEAASPFGP DLVPVAQRSE EPPSERGGIF GSDGKDFVDK DGEHFGKLHC AKRQQIMSNS ENAIEEQIAS NTTTTPQTFI STDDLLDCLV NPQVTRIVAQ LLIQGRSL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards