About Translation machinery-associated protein 16
Translation machinery-associated protein 16 (TMA16) is a protein
from Homo sapiens identified by UniProt accession
Q96EY4, 203 residues long.
MolForge cross-references it against 0 known binders and
15 disease associations.
Target properties
| Protein name | Translation machinery-associated protein 16 |
|---|
| UniProt accession | Q96EY4 |
|---|
| Gene | TMA16 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 203 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (15)
Diseases linked to this target (Open Targets).
- multiple sclerosis · score 0.07
- fat body mass · score 0.05
- urate measurement · score 0.05
- heel bone mineral density · score 0.04
- bone density · score 0.04
- body mass index · score 0.03
- adolescent idiopathic scoliosis · score 0.03
- colorectal cancer · score 0.02
- medulloblastoma · score 0.01
- hepatocellular carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96EY4-F1 | alphafold | PREDICTED | 82.53 | — |
Amino-acid sequence (203 residues)
MPKAPKGKSA GREKKVIHPY SRKAAQITRE AHKQEKKEKL KNEKALRLNL VGEKLQWFQN HLDPQKKRYS KKDACELIER YLNRFSSELE QIELHNSIRD RQGRRHCSRE TVIKQTMERE RQQFEGYGLE IPDILNASNL KTFREWDFDL KKLPNIKMRK ICANDAIPKT CKRKTIITVD QDLGELELND ESSDSDEEMT AVA
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