About Multivesicular body subunit 12A
Multivesicular body subunit 12A (MVB12A) is a protein
from Homo sapiens identified by UniProt accession
Q96EY5, 273 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | Multivesicular body subunit 12A |
|---|
| UniProt accession | Q96EY5 |
|---|
| Gene | MVB12A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 273 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (14)
Diseases linked to this target (Open Targets).
- HIV infection · score 0.53
- viral disease · score 0.46
- creatinine measurement · score 0.27
- body height · score 0.08
- HbA1c measurement · score 0.04
- glioblastoma multiforme · score 0.01
- astrocytoma · score 0.01
- oligodendroglioma · score 0.01
- COVID-19 · score 0.01
- Obesity · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96EY5-F1 | alphafold | PREDICTED | 77.26 | — |
Amino-acid sequence (273 residues)
MDPVPGTDSA PLAGLAWSSA SAPPPRGFSA ISCTVEGAPA SFGKSFAQKS GYFLCLSSLG SLENPQENVV ADIQIVVDKS PLPLGFSPVC DPMDSKASVS KKKRMCVKLL PLGATDTAVF DVRLSGKTKT VPGYLRIGDM GGFAIWCKKA KAPRPVPKPR GLSRDMQGLS LDAASQPSKG GLLERTASRL GSRASTLRRN DSIYEASSLY GISAMDGVPF TLHPRFEGKS CSPLAFSAFG DLTIKSLADI EEEYNYGFVV EKTAAARLPP SVS
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