About Small ribosomal subunit protein mS39
Small ribosomal subunit protein mS39 (PTCD3) is a protein
from Homo sapiens identified by UniProt accession
Q96EY7, 689 residues long.
MolForge cross-references it against 0 known binders and
37 disease associations.
Target properties
| Protein name | Small ribosomal subunit protein mS39 |
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| UniProt accession | Q96EY7 |
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| Gene | PTCD3 |
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| Organism | Homo sapiens |
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| Length | 689 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (37)
Diseases linked to this target (Open Targets).
- combined oxidative phosphorylation deficiency 51 · score 0.68
- genetic disorder · score 0.19
- metabolite measurement · score 0.08
- diastolic blood pressure · score 0.05
- hemoglobin D disease · score 0.05
- hemoglobin E-beta-thalassemia syndrome · score 0.05
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.04
- dominant beta-thalassemia · score 0.04
- delta-beta-thalassemia · score 0.04
- hemoglobin E disease · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96EY7-F1 | alphafold | PREDICTED | 78.97 | — |
Amino-acid sequence (689 residues)
MAVVSAVRWL GLRSRLGQPL TGRRAGLCEQ ARSCRFYSGS ATLSKVEGTD VTGIEEVVIP KKKTWDKVAV LQALASTVNR DTTAVPYVFQ DDPYLMPASS LESRSFLLAK KSGENVAKFI INSYPKYFQK DIAEPHIPCL MPEYFEPQIK DISEAALKER IELRKVKASV DMFDQLLQAG TTVSLETTNS LLDLLCYYGD QEPSTDYHFQ QTGQSEALEE ENDETSRRKA GHQFGVTWRA KNNAERIFSL MPEKNEHSYC TMIRGMVKHR AYEQALNLYT ELLNNRLHAD VYTFNALIEA TVCAINEKFE EKWSKILELL RHMVAQKVKP NLQTFNTILK CLRRFHVFAR SPALQVLREM KAIGIEPSLA TYHHIIRLFD QPGDPLKRSS FIIYDIMNEL MGKRFSPKDP DDDKFFQSAM SICSSLRDLE LAYQVHGLLK TGDNWKFIGP DQHRNFYYSK FFDLICLMEQ IDVTLKWYED LIPSAYFPHS QTMIHLLQAL DVANRLEVIP KIWKDSKEYG HTFRSDLREE ILMLMARDKH PPELQVAFAD CAADIKSAYE SQPIRQTAQD WPATSLNCIA ILFLRAGRTQ EAWKMLGLFR KHNKIPRSEL LNELMDSAKV SNSPSQAIEV VELASAFSLP ICEGLTQRVM SDFAINQEQK EALSNLTALT SDSDTDSSSD SDSDTSEGK
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