About Thialysine N-epsilon-acetyltransferase
Thialysine N-epsilon-acetyltransferase (SAT2) is a protein
from Homo sapiens identified by UniProt accession
Q96F10, 170 residues long.
MolForge cross-references it against 0 known binders and
45 disease associations.
Target properties
| Protein name | Thialysine N-epsilon-acetyltransferase |
|---|
| UniProt accession | Q96F10 |
|---|
| Gene | SAT2 |
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| Organism | Homo sapiens |
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| Length | 170 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (45)
Diseases linked to this target (Open Targets).
- serum metabolite measurement · score 0.19
- apolipoprotein A 1 measurement · score 0.15
- testosterone measurement · score 0.13
- sex hormone-binding globulin measurement · score 0.13
- Red cell distribution width · score 0.12
- heel bone mineral density · score 0.11
- BMI-adjusted waist-hip ratio · score 0.10
- blood protein measurement · score 0.10
- estradiol measurement · score 0.09
- waist-hip ratio · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96F10-F1 | alphafold | PREDICTED | 93.94 | — |
Amino-acid sequence (170 residues)
MASVRIREAK EGDCGDILRL IRELAEFEKL SDQVKISEEA LRADGFGDNP FYHCLVAEIL PAPGKLLGPC VVGYGIYYFI YSTWKGRTIY LEDIYVMPEY RGQGIGSKII KKVAEVALDK GCSQFRLAVL DWNQRAMDLY KALGAQDLTE AEGWHFFCFQ GEATRKLAGK
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