About Enhancer of mRNA-decapping protein 3
Enhancer of mRNA-decapping protein 3 (EDC3) is a protein
from Homo sapiens identified by UniProt accession
Q96F86, 508 residues long.
MolForge cross-references it against 0 known binders and
40 disease associations.
Target properties
| Protein name | Enhancer of mRNA-decapping protein 3 |
|---|
| UniProt accession | Q96F86 |
|---|
| Gene | EDC3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 508 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (40)
Diseases linked to this target (Open Targets).
- autosomal recessive non-syndromic intellectual disability · score 0.53
- neurodegenerative disease · score 0.39
- mean platelet volume · score 0.11
- thrombocytopenia 4 · score 0.04
- congenital anomalies of kidney and urinary tract 1 · score 0.04
- platelet-type bleeding disorder 15 · score 0.04
- macrothrombocytopenia, isolated, 2, autosomal dominant · score 0.04
- renal hypodysplasia/aplasia 3 · score 0.04
- familial juvenile hyperuricemic nephropathy type 2 · score 0.04
- bleeding disorder, platelet-type, 24 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96F86-F1 | alphafold | PREDICTED | 77.02 | — |
Amino-acid sequence (508 residues)
MATDWLGSIV SINCGDSLGV YQGRVSAVDQ VSQTISLTRP FHNGVKCLVP EVTFRAGDIT ELKILEIPGP GDNQHFGDLH QTELGPSGAG CQVGINQNGT GKFVKKPASS SSAPQNIPKR TDVKSQDVAV SPQQQQCSKS YVDRHMESLS QSKSFRRRHN SWSSSSRHPN QATPKKSGLK NGQMKNKDDE CFGDDIEEIP DTDFDFEGNL ALFDKAAVFE EIDTYERRSG TRSRGIPNER PTRYRHDENI LESEPIVYRR IIVPHNVSKE FCTDSGLVVP SISYELHKKL LSVAEKHGLT LERRLEMTGV CASQMALTLL GGPNRLNPKN VHQRPTVALL CGPHVKGAQG ISCGRHLANH DVQVILFLPN FVKMLESITN ELSLFSKTQG QQVSSLKDLP TSPVDLVINC LDCPENVFLR DQPWYKAAVA WANQNRAPVL SIDPPVHEVE QGIDAKWSLA LGLPLPLGEH AGRIYLCDIG IPQQVFQEVG INYHSPFGCK FVIPLHSA
Explore Enhancer of mRNA-decapping protein 3 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets