About Phosphoinositide-3-kinase-interacting protein 1
Phosphoinositide-3-kinase-interacting protein 1 (PIK3IP1) is a protein
from Homo sapiens identified by UniProt accession
Q96FE7, 263 residues long.
MolForge cross-references it against 0 known binders and
72 disease associations.
Target properties
| Protein name | Phosphoinositide-3-kinase-interacting protein 1 |
| UniProt accession | Q96FE7 |
| Gene | PIK3IP1 |
| Organism | Homo sapiens |
| Length | 263 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (72)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.26
- eosinophil percentage of leukocytes · score 0.21
- Red cell distribution width · score 0.19
- diet measurement · score 0.17
- neutrophil count · score 0.15
- body height · score 0.15
- leukocyte count · score 0.10
- cortical surface area measurement · score 0.10
- skin pigmentation · score 0.10
- sum of basophil and neutrophil counts · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q96FE7-F1 | alphafold | PREDICTED | 67.10 | — |
Amino-acid sequence (263 residues)
MLLAWVQAFL VSNMLLAEAY GSGGCFWDNG HLYREDQTSP APGLRCLNWL DAQSGLASAP VSGAGNHSYC RNPDEDPRGP WCYVSGEAGV PEKRPCEDLR CPETTSQALP AFTTEIQEAS EGPGADEVQV FAPANALPAR SEAAAVQPVI GISQRVRMNS KEKKDLGTLG YVLGITMMVI IIAIGAGIIL GYSYKRGKDL KEQHDQKVCE REMQRITLPL SAFTNPTCEI VDEKTVVVHT SQTPVDPQEG TTPLMGQAGT PGA
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