Phosphoinositide-3-kinase-interacting protein 1 (PIK3IP1)

Homo sapiens — UniProt Q96FE7

Gene: PIK3IP1Homo sapiensSwissProt reviewed

About Phosphoinositide-3-kinase-interacting protein 1

Phosphoinositide-3-kinase-interacting protein 1 (PIK3IP1) is a protein from Homo sapiens identified by UniProt accession Q96FE7, 263 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.

Target properties

Protein namePhosphoinositide-3-kinase-interacting protein 1
UniProt accessionQ96FE7
GenePIK3IP1
OrganismHomo sapiens
Length263 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (72)

Diseases linked to this target (Open Targets).

  • eosinophil count · score 0.26
  • eosinophil percentage of leukocytes · score 0.21
  • Red cell distribution width · score 0.19
  • diet measurement · score 0.17
  • neutrophil count · score 0.15
  • body height · score 0.15
  • leukocyte count · score 0.10
  • cortical surface area measurement · score 0.10
  • skin pigmentation · score 0.10
  • sum of basophil and neutrophil counts · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q96FE7-F1alphafoldPREDICTED67.10—

Amino-acid sequence (263 residues)

MLLAWVQAFL VSNMLLAEAY GSGGCFWDNG HLYREDQTSP APGLRCLNWL DAQSGLASAP VSGAGNHSYC RNPDEDPRGP WCYVSGEAGV PEKRPCEDLR CPETTSQALP AFTTEIQEAS EGPGADEVQV FAPANALPAR SEAAAVQPVI GISQRVRMNS KEKKDLGTLG YVLGITMMVI IIAIGAGIIL GYSYKRGKDL KEQHDQKVCE REMQRITLPL SAFTNPTCEI VDEKTVVVHT SQTPVDPQEG TTPLMGQAGT PGA

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Quick facts

UniProtQ96FE7
GenePIK3IP1
OrganismHomo sapiens
Length263
Binders0
Diseases72
View on UniProt