About Sororin
Sororin (CDCA5) is a protein
from Homo sapiens identified by UniProt accession
Q96FF9, 252 residues long.
MolForge cross-references it against 0 known binders and
112 disease associations.
Target properties
| Protein name | Sororin |
|---|
| UniProt accession | Q96FF9 |
|---|
| Gene | CDCA5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 252 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (112)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.31
- reticulocyte count · score 0.16
- hepatocellular carcinoma · score 0.12
- neoplasm · score 0.11
- breast cancer · score 0.10
- urinary bladder cancer · score 0.10
- nonpapillary renal cell carcinoma · score 0.10
- cancer · score 0.09
- non-small cell lung carcinoma · score 0.08
- oral squamous cell carcinoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96FF9-F1 | alphafold | PREDICTED | 62.69 | — |
Amino-acid sequence (252 residues)
MSGRRTRSGG AAQRSGPRAP SPTKPLRRSQ RKSGSELPSI LPEIWPKTPS AAAVRKPIVL KRIVAHAVEV PAVQSPRRSP RISFFLEKEN EPPGRELTKE DLFKTHSVPA TPTSTPVPNP EAESSSKEGE LDARDLEMSK KVRRSYSRLE TLGSASTSTP GRRSCFGFEG LLGAEDLSGV SPVVCSKLTE VPRVCAKPWA PDMTLPGISP PPEKQKRKKK KMPEILKTEL DEWAAAMNAE FEAAEQFDLL VE
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