ELMO domain-containing protein 3 (ELMOD3)

About ELMO domain-containing protein 3

ELMO domain-containing protein 3 (ELMOD3) is a protein from Homo sapiens identified by UniProt accession Q96FG2, 381 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.

Target properties

Protein name	ELMO domain-containing protein 3
UniProt accession	Q96FG2
Gene	ELMOD3
Organism	Homo sapiens
Length	381 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (53)

Diseases linked to this target (Open Targets).

hearing loss, autosomal recessive · score 0.46
deafness · score 0.37
bone density · score 0.10
urate measurement · score 0.09
high density lipoprotein cholesterol measurement · score 0.09
attention deficit hyperactivity disorder · score 0.09
mean platelet volume · score 0.08
attention deficit-hyperactivity disorder 8 · score 0.07
schizophrenia 15 · score 0.07
lymphocyte percentage of leukocytes · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96FG2-F1	alphafold	PREDICTED	75.78	—

Amino-acid sequence (381 residues)

MNEKSCSFHS KEELRDGQGE RLSAGYSPSY DKDKSVLAFR GIPISELKNH GILQALTTEA YEWEPRVVST EVVRAQEEWE AVDTIQPETG SQASSEQPGQ LISFSEALQH FQTVDLSPFK KRIQPTIRRT GLAALRHYLF GPPKLHQRLR EERDLVLTIA QCGLDSQDPV HGRVLQTIYK KLTGSKFDCA LHGNHWEDLG FQGANPATDL RGAGFLALLH LLYLVMDSKT LPMAQEIFRL SRHHIQQFPF CLMSVNITHI AIQALREECL SRECNRQQKV IPVVNSFYAA TFLHLAHVWR TQRKTISDSG FVLKELEVLA KKSPRRLLKT LELYLARVSK GQASLLGAQK CYGPEAPPFK DLTFTGESDL QSHSSEGVWL I

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards