About BLOC-1-related complex subunit 8
BLOC-1-related complex subunit 8 (BORCS8) is a protein
from Homo sapiens identified by UniProt accession
Q96FH0, 119 residues long.
MolForge cross-references it against 0 known binders and
17 disease associations.
Target properties
| Protein name | BLOC-1-related complex subunit 8 |
|---|
| UniProt accession | Q96FH0 |
|---|
| Gene | BORCS8 |
|---|
| Organism | Homo sapiens |
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| Length | 119 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (17)
Diseases linked to this target (Open Targets).
- Immunodeficiency by defective expression of HLA class 2 · score 0.15
- MHC class II deficiency · score 0.15
- obsessive-compulsive symptom measurement · score 0.11
- mean arterial pressure · score 0.08
- diastolic blood pressure · score 0.08
- total blood protein measurement · score 0.07
- triglyceride measurement · score 0.06
- systolic blood pressure · score 0.06
- low density lipoprotein cholesterol measurement · score 0.03
- osteosarcoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96FH0-F1 | alphafold | PREDICTED | 92.38 | — |
Amino-acid sequence (119 residues)
MEEPEMQLKG KKVTDKFTES VYVLANEPSV ALYRLQEHVR RSLPELAQHK ADMQRWEEQS QGAIYTVEYA CSAVKNLVDS SVYFRSVEGL LKQAISIRDH MNASAQGHSP EEPPPPSSA
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