Secernin-2 (SCRN2)

About Secernin-2

Secernin-2 (SCRN2) is a protein from Homo sapiens identified by UniProt accession Q96FV2, 425 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.

Target properties

Protein name	Secernin-2
UniProt accession	Q96FV2
Gene	SCRN2
Organism	Homo sapiens
Length	425 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (24)

Diseases linked to this target (Open Targets).

hair color · score 0.16
body fat distribution · score 0.09
Constipation · score 0.09
skin pigmentation · score 0.07
drug use measurement · score 0.07
balding measurement · score 0.05
prostate carcinoma · score 0.04
asthma · score 0.04
type 2 diabetes mellitus · score 0.03
mean corpuscular volume · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96FV2-F1	alphafold	PREDICTED	94.38	—

Amino-acid sequence (425 residues)

MASSSPDSPC SCDCFVSVPP ASAIPAVIFA KNSDRPRDEV QEVVFVPAGT HTPGSRLQCT YIEVEQVSKT HAVILSRPSW LWGAEMGANE HGVCIGNEAV WTKEPVGEGE ALLGMDLLRL ALERSSSAQE ALHVITGLLE HYGQGGNCLE DAAPFSYHST FLLADRTEAW VLETAGRLWA AQRIQEGARN ISNQLSIGTD ISAQHPELRT HAQAKGWWDG QGAFDFAQIF SLTQQPVRME AAKARFQAGR ELLRQRQGGI TAEVMMGILR DKESGICMDS GGFRTTASMV SVLPQDPTQP CVHFLTATPD PSRSVFKPFI FGMGVAQAPQ VLSPTFGAQD PVRTLPRFQT QVDRRHTLYR GHQAALGLME RDQDRGQQLQ QKQQDLEQEG LEATQGLLAG EWAPPLWELG SLFQAFVKRE SQAYA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards